NAD+ IV Dosage Guide: 250mg vs 500mg vs 750mg vs 1000mg
So you have decided to try NAD+ therapy. Good. Now you are staring at four dose options and a price range from $350 to $900, wondering if you are about to underbuy or overpay.
This guide walks you through every NAD+ IV dosage level, who each one actually fits, and how to choose a starting point without guessing.
One thing first: this is a map, not a prescription. Your nurse reviews your health history and goals before any drip starts, and the final call is a conversation, not a menu order.
How NAD+ Dosing Works
NAD+ dosing is not “more is automatically better.” It is about matching the dose to your goal and your experience level.
Think of it like training. A beginner does not walk in and load the bar with their goal max. You start where your body can work with it, see how you respond, and build. NAD+ works the same way, and your response to your first drip tells your nurse a lot about where you should go next.
Two levers matter with every NAD+ IV dosage: how much, and how fast. Higher doses take longer to infuse comfortably, usually 2 to 4 hours total. Since we are mobile across Pinellas, Pasco, and Hillsborough counties, those hours happen on your couch, not in a clinic chair.
NAD+ 250mg: The Starting Point ($350)
Who it fits: First-timers, anyone easing back into NAD+ after a long break, and clients on a maintenance schedule after a loading phase.
250mg is the smart first drip. It is enough to feel what NAD+ does for your energy and clarity, while letting your nurse see how your body handles the infusion. Most people tolerate it easily, and it runs on the shorter end, around 2 hours.
If you are NAD-curious but not sure, start here. Nobody has ever regretted a sensible first dose. Plenty of people have regretted going big before their body knew what NAD+ felt like.
NAD+ 500mg: The Sweet Spot ($550)
Who it fits: People chasing focus, mental clarity, and sustained energy. Professionals fighting brain fog. Clients who did 250mg, liked it, and want more from each session.
500mg is our most popular dose, and for good reason. It is where most people report the clearest cognitive effects: sharper focus, better mood, steadier energy across the day. If your goal is performing better at work or feeling like your brain got a software update, this is your level.
Plan for 2 to 3 hours of infusion time.
NAD+ 750mg: The Recovery Dose ($750)
Who it fits: Serious athletes and lifters, people recovering from burnout or long-term stress, and clients building a deeper cellular repair protocol.
At 750mg you are past “boost” territory and into meaningful support for recovery and repair. This is the dose for people asking more from their bodies than most: heavy training blocks, brutal work seasons, or climbing back from running on empty for years.
Expect 3 to 4 hours, with your nurse pacing the drip to keep you comfortable the whole way.
NAD+ 1000mg: The Full Protocol ($900)
Who it fits: Experienced NAD+ clients committed to a maximum longevity and repair protocol.
1000mg is the top of the ladder, and it is earned, not bought. We generally recommend working up to this level over multiple sessions rather than starting here. Your body’s response at lower doses tells your nurse whether the full protocol makes sense for you.
For clients who use it, 1000mg anchors a serious longevity practice, usually on a recurring schedule. Infusion runs 3 to 4 hours.
Which NAD+ Dose Should You Start With?
The honest cheat sheet:
| Your Situation | Start Here |
| Never done NAD+ before | 250mg |
| Tried it, want cognitive effects | 500mg |
| Athlete or deep recovery goals | 500mg, move to 750mg |
| Building a longevity protocol | Work up toward 750mg or 1000mg |
| Monthly maintenance after loading | 250mg or 500mg |
The pattern most clients follow: start at 250mg or 500mg, run a loading phase of several drips over a few weeks, then settle into monthly maintenance. Your nurse will map this with you at your first session.
Can You Add Anything to a NAD+ Drip?
Yes, and one add-on is worth knowing about. The Ultimate Drip can be added to any NAD+ infusion for $179, down from its regular $369. It layers high-dose vitamin C, zinc, glutathione, amino acids, biotin, folic acid, and selenium on top of your NAD+, turning one session into full-spectrum cellular support.
If you are already committing 3 hours to a drip, stacking it is the efficient move. One appointment, complete coverage.
NAD+ Dosage FAQ
Can I just start at 1000mg to get it over with? You can ask, but your nurse will probably talk you down, and you will thank them. First-timers do better starting lower, and higher doses are more comfortable once your body knows the routine.
Does a higher dose mean a longer drip? Generally yes. NAD+ infuses slowly for comfort, so bigger doses take more time. See our full guide on how long a NAD+ drip takes.
How often should I get NAD+? Common pattern: a loading phase of several sessions in the first few weeks, then monthly maintenance. Your goals set the schedule.
Is the higher dose safe? All our NAD+ doses are administered by a licensed nurse who screens your health history first and monitors you throughout. Dose recommendations come from that screening, not from what is in your cart.
Can I change doses between sessions? Absolutely. Moving up or down between sessions based on your response is exactly how a good protocol works.
Start Where You Are
You do not need to pick the perfect dose today. Book a session, talk it through with your nurse, and start at the level that fits your body and your goals. The ladder will still be there.
Book Your NAD+ Drip or call (727) 425-1936. Mobile everywhere in Pinellas, Pasco, and Hillsborough counties.
Coastal Nurse IV Therapy provides nurse-delivered mobile IV services throughout the Tampa Bay area. This article is for education only and is not medical advice. Dosing decisions are made with a licensed professional based on your individual health history.